In this category

Specify a Date Range

Image #00008059

Erythroid karyorrhexis in myelodysplasia: bone marrow aspirate - 1.

A 47-year-old female was evaluated for easy bruising, menorrhagia, and anemia. The CBC revealed: WBC 1.4/µL, Hgb 8.8 g/dL and platelets 15,000/µL. Family history was negative for hematologic diseases and the physical examination was unremarkable. Bone marrow aspiration was hypercellular with prominent dyserythropoesis, dysmegakaryopoesis and dysgranulopoesis with less than 5% blasts. The chromosomal complement was 46,XX. The diagnosis of myelodysplasia was established and treatment was started with danazol, 200 mg twice daily and prednisone 1 mg/kg. The counts normalized except for the hemoglobin which remained at 10 g/dL. Follow up bone marrow revealed more prominent dyserythropoesis with striking karyorrhexis which is shown above in a Wright-Giemsa stained bone marrow aspirate.

Author: Jean Fradera
Date Added: 04/01/2008
Size: 00.4MB
Views: 0
Categories: Myelodysplastic Syndromes

This image will be permanently deleted and cannot be recovered. Are you sure?